YE6144
YE6144 is a selective small molecule inhibitor of IRF5 phosphorylation and also potently suppresses type I interferon production (IC50 = 0.09 μM) . This compound is a valuable research tool for studying IRF5-driven inflammatory and autoimmune pathways in both cellular and animal models.
Product Specifications
CAS Number
3065657-02-2
Product Name Alternative
YE 6144
Field of Research
Immunology & Inflammation
Solubility
DMSO:55 mg/mL (122.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (22.32 mM)
Smiles
C (=C/C1=CC=C (N=N1) N2CCOCC2) \C=3C=4C (=CC (F) =C (NC[C@H] (CC) N) C4) NN3.Cl
Molecular Formula
C21H27ClFN7O
Molecular Weight
447.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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