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PDE5-IN-3

PDE5-IN-3 is a potent, dual-targeting small molecule with low nanomolar PDE5 inhibition and moderate EGFR activity. It significantly suppresses the Wnt/β-catenin pathway and induces intrinsic apoptosis in HepG2 cells, demonstrating notable in vitro antitumor effects for oncology research.

Product Specifications

CAS Number

2538149-57-2

Field of Research

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Smiles

O=C1C2=C (N (N=C2) C3=CC=C (Br) C=C3) NC (=N1) C=4C (OC) =NC5=C (C4) C=CC=C5

Molecular Formula

C21H14BrN5O2

Molecular Weight

448.27

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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