PDE5-IN-3
PDE5-IN-3 is a potent, dual-targeting small molecule with low nanomolar PDE5 inhibition and moderate EGFR activity. It significantly suppresses the Wnt/β-catenin pathway and induces intrinsic apoptosis in HepG2 cells, demonstrating notable in vitro antitumor effects for oncology research.
Product Specifications
CAS Number
2538149-57-2
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C1C2=C (N (N=C2) C3=CC=C (Br) C=C3) NC (=N1) C=4C (OC) =NC5=C (C4) C=CC=C5
Molecular Formula
C21H14BrN5O2
Molecular Weight
448.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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