Senexin C
Senexin C is a potent and selective CDK8/19 inhibitor with oral bioavailability, demonstrating improved metabolic stability and potency over Senexin B. It exhibits anticancer activity by inhibiting the proliferation of MV4-11 leukemia cells in vitro, supporting its investigation in oncology research.
Product Specifications
CAS Number
2375554-02-0
Product Name Alternative
CDK19, CDK8
Field of Research
Cell Biology
Purity
97.91% (May vary between batches)
Solubility
DMSO:20 mg/mL (44.49 mM) ;10% DMSO+90% Saline:2 mg/mL (4.45 mM)
Smiles
N#CC=1C=CC2=NC=CC (NCCC=3C=CC4=CC (=CC=C4C3) C (=O) N5CCN (C) CC5) =C2C1
Molecular Formula
C28H27N5O
Molecular Weight
449.55
Storage Conditions
-20°C
Notes
For research use only.
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