BTK-IN-10
BTK-IN-10 is a highly potent small molecule inhibitor effective against both wild-type and C481S mutant Bruton's tyrosine kinase (BTK), with IC50 values below 5 nM. It serves as a valuable chemical probe for studying B-cell receptor signaling in hematological malignancies, applicable in both cellular assays and in vivo research models.
Product Specifications
CAS Number
2758596-07-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
NC=1C2=C (N=C (N2C=CN1) C3CCC (CO) OC3) C4=CC=C (C (F) (F) C5=CC=CC=C5) C=C4
Molecular Formula
C25H24F2N4O2
Molecular Weight
450.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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