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BTK-IN-10

BTK-IN-10 is a highly potent small molecule inhibitor effective against both wild-type and C481S mutant Bruton's tyrosine kinase (BTK), with IC50 values below 5 nM. It serves as a valuable chemical probe for studying B-cell receptor signaling in hematological malignancies, applicable in both cellular assays and in vivo research models.

Product Specifications

CAS Number

2758596-07-3

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

NC=1C2=C (N=C (N2C=CN1) C3CCC (CO) OC3) C4=CC=C (C (F) (F) C5=CC=CC=C5) C=C4

Molecular Formula

C25H24F2N4O2

Molecular Weight

450.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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