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RIPK1-IN-12

RIPK1-IN-12 is a highly potent and selective RIPK1 inhibitor, demonstrating low nanomolar EC50 values in blocking necroptosis in both human and murine cellular models. This tool compound is widely used in preclinical research to investigate RIPK1-driven inflammatory and degenerative pathways in vitro and in animal models of disease.

Product Specifications

CAS Number

2173556-92-6

Field of Research

Cell Biology, Signal Transduction

Smiles

N (C (=O) C1CC1) C=2SC=3C (N2) =CC=C (C3) C=4C=C (NC (OC5CCCCC5) =O) C (C) =NC4

Molecular Formula

C24H26N4O3S

Molecular Weight

450.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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