ROMK-IN-32
ROMK-IN-32 is a selective small-molecule inhibitor of the renal outer medullary potassium (ROMK) channel with an IC50 of 35 nM, exhibiting significant selectivity over the hERG channel (IC50 = 22 μM) . This compound is a valuable pharmacological tool for in vitro and in vivo research into renal physiology, electrolyte balance, and diuretic mechanisms.
Product Specifications
CAS Number
1914944-54-9
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C1C2 (CCN1C3=NN (C) C (=O) C=C3) CCN (C[C@H] (O) C=4C (C) =C5C (=CC4) C (=O) OC5) CC2
Molecular Formula
C24H28N4O5
Molecular Weight
452.5
Storage Conditions
-20°C
Notes
For research use only.
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