JH-XIV-68-3
JH-XIV-68-3 is a macrocyclic compound functioning as a selective biochemical and cellular inhibitor of DYRK1A and DYRK1B kinases. It demonstrates antitumor activity in head and neck squamous cell carcinoma (HNSCC) models, supporting its use as a research tool for studying DYRK family biology in oncology.
Product Specifications
CAS Number
2426628-52-4
Field of Research
Cell Biology, Signal Transduction
Smiles
C (#N) C1=C2C (=NN1C) N (C) C (=O) CCCN3C=C (C=4C5=CC2=CN=C5NC4) C (C (F) (F) F) =N3
Molecular Formula
C21H17F3N8O
Molecular Weight
454.41
Storage Conditions
-20°C
Notes
For research use only.
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