Migoprotafib
Migoprotafib (GDC-1971) is a potent, selective SHP2 phosphatase inhibitor used in cancer research. It is applied in studies of advanced solid tumors, enabling both in vitro biochemical assays and in vivo efficacy models to investigate RTK and MAPK pathway signaling.
Product Specifications
CAS Number
2377352-49-1
Product Name Alternative
GDC1971, GDC-1971, RG 6433, RLY-1971, RO-7517834
Field of Research
Metabolism Research, Signal Transduction
Purity
98.31% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.26 mM) ; DMSO:80 mg/mL (176.01 mM)
Smiles
N[C@H]1C2 (OC=3C1=CC=CC3) CCN (CC2) C=4N=C5C (=NC4) C (=NN5) N6C=7C (CCC6) =NC=CC7
Molecular Formula
C25H26N8O
Molecular Weight
454.53
Storage Conditions
-20°C
Notes
For research use only.
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