NVP-CLR457
NVP-CLR457 (compound 40) is an orally bioavailable, balanced pan-class I PI3K inhibitor demonstrating antitumor activity. Its efficacy is supported by a clear dose-dependent pharmacokinetic/pharmacodynamic relationship observed in preclinical studies, making it a useful tool for investigating PI3K signaling in cancer research models.
Product Specifications
CAS Number
1453082-52-4
Field of Research
Signal Transduction
Smiles
C (O) [C@@H]1N (C (=O) O[C@@H]1C) C=2C=C (N=C (N2) N3CCOCC3) C=4C (C (F) (F) F) =NC (N) =NC4
Molecular Formula
C18H20F3N7O4
Molecular Weight
455.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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