AMG 837 hemicalcium
AMG 837 hemicalcium is a potent and orally bioavailable partial agonist of the GPR40 (FFA1) receptor, demonstrating high binding affinity (pIC50: 8.13) . It has been shown to stimulate glucose-dependent insulin secretion in vitro and reduce blood glucose levels in rodent models, supporting its use in diabetes research.
Product Specifications
CAS Number
1291087-14-3
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CC#C[C@@H] (CC (=O) [O-]) C1=CC=C (C=C1) OCC2=CC (=CC=C2) C3=CC=C (C=C3) C (F) (F) F.CC#C[C@@H] (CC (=O) [O-]) C1=CC=C (C=C1) OCC2=CC (=CC=C2) C3=CC=C (C=C3) C (F) (F) F.[Ca+2]
Molecular Formula
C52H40CaF6O6
Molecular Weight
914.954
Storage Conditions
-20°C
Notes
For research use only.
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