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UNC9994 hydrochloride

UNC9994 hydrochloride is a β-arrestin-biased agonist of the dopamine D2 receptor (D2R) with a Ki of 79 nM. It acts as a Gi-regulated antagonist of cAMP production while potently stimulating D2R/β-arrestin-2 signaling, leading to observed psychostimulatory effects in research models. This profile makes it a valuable tool for studying biased signaling in neuropharmacology, particularly in psychiatric and neurological disorders.

Product Specifications

CAS Number

2108826-33-9

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

Cl.ClC1=CC=CC (=C1Cl) C2CCN (CCCOC=3C=CC=4SC=NC4C3) CC2

Molecular Formula

C21H23Cl3N2OS

Molecular Weight

457.84

Storage Conditions

-20°C

Notes

For research use only.

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