NBTIs-IN-5
NBTIs-IN-5 (Compound 5r) is a novel bacterial topoisomerase inhibitor targeting Mycobacterium abscessus DNA gyrase with an IC50 of 1.5 μM. It demonstrates potent antibacterial activity with a MIC90 of 0.4 μM, making it a valuable tool for in vitro studies of nontuberculous mycobacterial infections and novel antibiotic mechanisms.
Product Specifications
CAS Number
2767443-78-5
Field of Research
Infectious Disease & Virology
Smiles
N (C (=O) [C@@H]1CC[C@@H] (NCC2=CC=C (C (F) (F) F) C=C2) CC1) C=3C4=C (C=CC (OC) =N4) N=CC3
Molecular Formula
C24H25F3N4O2
Molecular Weight
458.48
Storage Conditions
-20°C
Notes
For research use only.
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