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Ezurpimtrostat hydrochloride

Ezurpimtrostat hydrochloride (GNS561 hydrochloride) is an orally bioavailable, small-molecule inhibitor of palmitoyl-protein thioesterase 1 (PPT1) . It exerts anticancer and antifibrotic activity by blocking late-stage autophagy, leading to lysosomal dysfunction and the inhibition of cancer cell proliferation, as demonstrated in in vitro and in vivo studies.

Product Specifications

CAS Number

1914148-73-4

Product Name Alternative

Antiviral, GNS561 hydrochloride

Field of Research

Cell Biology, Immunology & Inflammation

Purity

99.84% (May vary between batches)

Solubility

DMSO:5 mg/mL (10.88 mM)

Smiles

Cl.CC (C) (C) NC1CCN (CC1) c1cc (NCc2ccc (Cl) cc2) nc2ccccc12

Molecular Formula

C25H32Cl2N4

Molecular Weight

459.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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