Ezurpimtrostat hydrochloride
Ezurpimtrostat hydrochloride (GNS561 hydrochloride) is an orally bioavailable, small-molecule inhibitor of palmitoyl-protein thioesterase 1 (PPT1) . It exerts anticancer and antifibrotic activity by blocking late-stage autophagy, leading to lysosomal dysfunction and the inhibition of cancer cell proliferation, as demonstrated in in vitro and in vivo studies.
Product Specifications
CAS Number
1914148-73-4
Product Name Alternative
Antiviral, GNS561 hydrochloride
Field of Research
Cell Biology, Immunology & Inflammation
Purity
99.84% (May vary between batches)
Solubility
DMSO:5 mg/mL (10.88 mM)
Smiles
Cl.CC (C) (C) NC1CCN (CC1) c1cc (NCc2ccc (Cl) cc2) nc2ccccc12
Molecular Formula
C25H32Cl2N4
Molecular Weight
459.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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