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MtTMPK-IN-3

MtTMPK-IN-3 is a potent and selective inhibitor of Mycobacterium tuberculosis thymidylate kinase (IC50 = 0.12 μM), exhibiting antitubercular activity against Mtb H37Rv (MIC = 12.5 μM) . This small molecule is a valuable chemical tool for in vitro studies in tuberculosis drug discovery research, despite showing cytotoxicity in MRC-5 cells at 12.5 μM.

Product Specifications

CAS Number

2799607-80-8

Field of Research

Cell Biology, Infectious Disease & Virology, Molecular Biology

Smiles

O=C1N (C2CCN (CC3=CC (OC4=CC (Cl) =CC (Cl) =C4) =CC=C3) CC2) C=C (C) C (=O) N1

Molecular Formula

C23H23Cl2N3O3

Molecular Weight

460.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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