Tau-aggregation and neuroinflammation-IN-1
Tau-aggregation and neuroinflammation-IN-1 is a potent dual-action compound that inhibits both tau protein aggregation (including AcPHF6 and full-length tau) and neuroinflammation by reducing NO release. It exhibits low cytotoxicity in BV2 microglial cells and has been shown to reverse memory deficits in an okadaic acid-induced rat model of neurodegeneration.
Product Specifications
CAS Number
2175953-98-5
Product Name Alternative
NOSynthase, Microtubule Associated, MicrotubuleAssociated, NO, NO Synthase, Tau aggregation
Field of Research
Immunology & Inflammation, Neuroscience, Signal Transduction
Purity
99.85% (May vary between batches)
Solubility
DMSO:50 mg/mL (108.59 mM)
Smiles
C[C@@]12C=3C (OC1=CC4=C (C2=O) C (C) =NN4C5=CC=C (C (O) =O) C=C5) =C (C (C) =O) C (O) =C (C) C3O
Molecular Formula
C25H20N2O7
Molecular Weight
460.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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