NDI-034858
NDI-034858 (TAK-279) is a potent, selective TYK2 pseudokinase (JH2) domain inhibitor with sub-nanomolar affinity. It is a research tool for investigating IL-12/IL-23 signaling pathways in autoimmune disease models, supporting both in vitro mechanistic studies and in vivo preclinical research.
Product Specifications
CAS Number
2272904-53-5
Product Name Alternative
ILReceptor, IL-23, IL Receptor, IL-12, NDI 03485, NDI 034858, NDI03485, NDI034858, NDI-034858, Tyk2 JH2, Tyrosine Kinases, TyrosineKinases, TAK 279, TAK279, TAK-279
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Purity
>99.99% (May vary between batches)
Solubility
DMSO:45 mg/mL (97.72 mM)
Smiles
CNc1cc (Nc2cccn (-c3ccccn3) c2=O) nc2c (cnn12) C (=O) N[C@@H]1CC[C@H]1OC
Molecular Formula
C23H24N8O3
Molecular Weight
460.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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