GEM144
GEM144 is an orally bioavailable small molecule that dually inhibits POLA1 and HDAC11. This activity induces p53 acetylation and p21 expression, leading to G1/S cell cycle arrest and apoptosis, making it a useful research tool for oncology studies in both cellular and animal models.
Product Specifications
CAS Number
2487526-28-1
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
98.10% (May vary between batches)
Smiles
O (C (C (NO) =O) C) C1=C (C23CC4CC (C2) CC (C3) C4) C=C (C=C1) C5=CC=C (/C=C/C (O) =O) C=C5
Molecular Formula
C28H31NO5
Molecular Weight
461.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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