SOS1-IN-7
SOS1-IN-7 (compound 18-p1) is a potent small molecule SOS1 inhibitor, demonstrating activity against SOS1-G12D (IC50 20 nM) and SOS1-G12V (IC50 67 nM) . This research compound is a valuable tool for investigating KRAS-driven cancers in both cellular and animal models, aiding the study of RAS/MAPK pathway signaling.
Product Specifications
CAS Number
2755415-30-4
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
N ([C@H] (C) C1=C (F) C (C (F) F) =CC=C1) C2=C3C (=NC (=O) C (=C3) [C@]4 (O) CC[C@@H] (O) CC4) NC (C) =N2
Molecular Formula
C23H25F3N4O3
Molecular Weight
462.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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