RLX-33
RLX-33 is a brain-penetrant, selective RXFP3 antagonist that inhibits relaxin 3-mediated ERK1/2 phosphorylation. It effectively suppresses R3/I5-induced feeding in rats, making it a valuable research tool for studying central metabolic regulation, appetite control, and related disorders.
Product Specifications
CAS Number
2784577-71-3
Product Name Alternative
ERK1, ERK2, RXFP receptor, RXFPreceptor
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.82% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (7.13 mM) ; DMSO:112.5 mg/mL (243.04 mM)
Smiles
N (C (=O) C1CN (CC2=CC=CO2) C (=O) C1) C3=CC=C (C4=NC (=NO4) C5=CC=C (Cl) C=C5) C=C3
Molecular Formula
C24H19ClN4O4
Molecular Weight
462.89
Storage Conditions
-20°C
Notes
For research use only.
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