MRK-740
MRK-740 is a potent, selective small-molecule inhibitor of the PRDM9 histone methyltransferase, effectively suppressing PRDM9-dependent H3K4 trimethylation. This tool compound is valuable for investigating meiosis, recombination hotspots, and epigenetic regulation in both cellular and biochemical studies.
Product Specifications
CAS Number
2387510-80-5
Product Name Alternative
HistoneMethyltransferase, Histone Methyltransferase
Field of Research
Epigenetics & Chromatin
Purity
99.66% (May vary between batches)
Solubility
DMSO:30 mg/mL (64.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.31 mM)
Smiles
COc1cc (OC) cc (c1) -c1noc (n1) N1CCN (C) C2 (CCN (CC2) c2ccnc (C) c2) C1
Molecular Formula
C25H32N6O3
Molecular Weight
464.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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