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MRK-740

MRK-740 is a potent, selective small-molecule inhibitor of the PRDM9 histone methyltransferase, effectively suppressing PRDM9-dependent H3K4 trimethylation. This tool compound is valuable for investigating meiosis, recombination hotspots, and epigenetic regulation in both cellular and biochemical studies.

Product Specifications

CAS Number

2387510-80-5

Product Name Alternative

HistoneMethyltransferase, Histone Methyltransferase

Field of Research

Epigenetics & Chromatin

Purity

99.66% (May vary between batches)

Solubility

DMSO:30 mg/mL (64.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.31 mM)

Smiles

COc1cc (OC) cc (c1) -c1noc (n1) N1CCN (C) C2 (CCN (CC2) c2ccnc (C) c2) C1

Molecular Formula

C25H32N6O3

Molecular Weight

464.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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