TDP1 Inhibitor-2
TDP1 Inhibitor-2 is a potent small molecule targeting tyrosyl-DNA phosphodiesterase 1 (TDP1) with an IC50 of 99 nM, and it also inhibits the SCAN1-associated mutant TDP1 (IC50: 3.5 μM) . This compound is a valuable chemical probe for studying DNA repair mechanisms and TDP1-related neurodegenerative diseases in both cellular and biochemical assays.
Product Specifications
CAS Number
859142-95-3
Field of Research
Epigenetics & Chromatin; Pharmacology & Drug Discovery, Metabolism Research
Smiles
O=C1C (C=2C=3C (=CC (OCC4=C (Cl) C=CC=C4Cl) =CC3) OC (=O) C2) =CC=5C (O1) =CC=CC5
Molecular Formula
C25H14Cl2O5
Molecular Weight
465.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS751950-01 48 Well
Sheep Glutamate Cysteine Ligase Catalytic subunit ELISA Kit
Sign In for Pricing
View Details MBS751950-02 96 Well
Sheep Glutamate Cysteine Ligase Catalytic subunit ELISA Kit
Sign In for Pricing
View Details MBS751950-03 5x 96 Well
Sheep Glutamate Cysteine Ligase Catalytic subunit ELISA Kit
Sign In for Pricing
View Details MBS751950-04 10x 96 Well
Sheep Glutamate Cysteine Ligase Catalytic subunit ELISA Kit
Sign In for Pricing
View Details 
LV772200 1.0 µg DNA
OFD1P13Y Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details MBS6345442-01 0.1 mL
SCUBE2, ID (N266) (SCUBE2, CEGP1, Signal peptide, CUB and EGF-like domain-containing protein 2, Protein CEGP1) (MaxLight 405)
Sign In for Pricing
View Details