Carbonic anhydrase inhibitor 5

Carbonic anhydrase inhibitor 5 is a potent and selective small molecule targeting human carbonic anhydrases, with IC50 values of 42.9 nM for hCA II, 47.6 nM for hCA IX, and 6.7 nM for hCA XII. This compound is a valuable research tool for investigating the role of these isoforms, particularly the tumor-associated hCA IX and XII, in cancer biology and hypoxic signaling using in vitro and cellular models.