CCG-271423
CCG-271423 is a potent, selective GRK5 inhibitor (IC50 = 2.1 nM) with significant selectivity over GRK2. This small molecule is a valuable research tool for investigating GRK5's role in cardiac cell signaling, as it reduces calcium transients and contractility in cardiomyocyte studies.
Product Specifications
CAS Number
2750413-88-6
Field of Research
Pharmacology & Drug Discovery
Smiles
C (=C\1/C=2C (NC1=O) =CC=C (C (N[C@H] (C) C3=CC=CC=C3) =O) C2) \C4=C (C) C (C (NCC#C) =O) =C (C) N4
Molecular Formula
C28H26N4O3
Molecular Weight
466.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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