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10-Formyl-5,8-dideazafolic acid

This small molecule serves as a substrate for 10-formyltetrahydrofolate dehydrogenase and acts as an inhibitor of thymidylate synthase. It is used in biochemical research to study folate metabolism, nucleotide biosynthesis, and for evaluating potential anticancer strategies in vitro.

Product Specifications

CAS Number

61038-31-1

Product Name Alternative

DNASynthesis, DNA Synthesis, RNASynthesis, RNA Synthesis, Thymidylate Synthase

Field of Research

Cell Biology, Molecular Biology

Purity

96.04% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.14 mM) ; DMSO:60 mg/mL (128.36 mM)

Smiles

Nc1nc (=O) c2cc (CN (C=O) c3ccc (cc3) C (=O) N[C@@H] (CCC (O) =O) C (O) =O) ccc2[nH]1

Molecular Formula

C22H21N5O7

Molecular Weight

467.43

Storage Conditions

-20°C

Notes

For research use only.

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