Dyrk1A-IN-8
Product Specifications
UNSPSC Description
Dyrk1A-IN-8 (compound 4C) is a potent inhibitor of Dyrk1A , with the IC50 of 209 nM. Dyrk1A-IN-8 plays an important role in neurodegenerative diseases[1].
Target Antigen
DYRK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dyrk1a-in-8.html
Solubility
10 mM in DMSO
Smiles
CC1=NC=CC2=C1N(C3=CC(OC)=CC=C32)CCN(C)C
Molecular Weight
283.37
References & Citations
[1]Hunter T Warren, et al. Psychoplastogenic DYRK1A Inhibitors with Therapeutic Effects Relevant to Alzheimer’s Disease. J Med Chem. 2024 May 9;67(9):6922-6937.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158212/Dyrk1A-IN-8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158212/
Clinical Information
No Development Reported
CAS Number
101578-13-6
Curated Selection
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