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Dyrk1A-IN-8

Dyrk1A-IN-8 (compound 4C) is a potent inhibitor of Dyrk1A , with the IC50 of 209 nM. Dyrk1A-IN-8 plays an important role in neurodegenerative diseases[1].

Product Specifications

CAS Number

101578-13-6

UNSPSC

12352005

Target

DYRK

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dyrk1a-in-8.html

Solubility

10 mM in DMSO

Smiles

CC1=NC=CC2=C1N(C3=CC(OC)=CC=C32)CCN(C)C

Molecular Formula

C17H21N3O

Molecular Weight

283.37

References & Citations

[1]Hunter T Warren, et al. Psychoplastogenic DYRK1A Inhibitors with Therapeutic Effects Relevant to Alzheimer’s Disease. J Med Chem. 2024 May 9;67 (9) :6922-6937.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DYRK1

Frequently Asked Questions

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