Dyrk1A-IN-8
Dyrk1A-IN-8 (compound 4C) is a potent inhibitor of Dyrk1A , with the IC50 of 209 nM. Dyrk1A-IN-8 plays an important role in neurodegenerative diseases[1].
Product Specifications
CAS Number
[101578-13-6]
UNSPSC
12352005
Target
DYRK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dyrk1a-in-8.html
Solubility
10 mM in DMSO
Smiles
CC1=NC=CC2=C1N(C3=CC(OC)=CC=C32)CCN(C)C
Molecular Formula
C17H21N3O
Molecular Weight
283.37
References & Citations
[1]Hunter T Warren, et al. Psychoplastogenic DYRK1A Inhibitors with Therapeutic Effects Relevant to Alzheimer’s Disease. J Med Chem. 2024 May 9;67 (9) :6922-6937.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DYRK1
Curated Selection
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