COX-2/15-LOX-IN-1
COX-2/15-LOX-IN-1 (Compound 14) is a dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 0.075 μM) and 15-lipoxygenase (15-LOX; IC50 = 2.98 μM), with significant selectivity over COX-1. This small molecule exhibits anti-inflammatory activity and is a useful research tool for studying eicosanoid pathways in both cellular and animal models of inflammation.
Product Specifications
CAS Number
2413565-15-6
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience
Smiles
S (C) C=1N (C=2C (N1) =CC=CC2) C=3N=C (NCC (=NNC (NC4=CC=CC=C4) =S) C) SC3
Molecular Formula
C21H21N7S3
Molecular Weight
467.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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