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CCT128930

CCT128930 is a potent and selective ATP-competitive Akt2 inhibitor, exhibiting an IC50 of 6 nM and 28-fold selectivity over PKA. This small molecule is a valuable research tool for studying Akt2 signaling in cancer metabolism and proliferation, with applications in both in vitro biochemical assays and cellular pathway analysis.

Product Specifications

CAS Number

885499-61-6

Product Name Alternative

Cell, CCT 128930, CCT128930, CCT-128930, breast cancer, DNA, cycle, damage, Akt, Akt2, Apoptosis, arrest, Autophagy, BT474, p70 S6K, inhibit, Inhibitor, glioblastoma, growth, PKA, PKB, phosphorylation, selective, Protein kinase B, PTEN, S6Kinase, S6 Kinase, U87MG

Field of Research

Cell Biology, Signal Transduction

Purity

99.07% (May vary between batches)

Solubility

Ethanol:6 mg/mL (17.55 mM) ; H2O:<1 mg/mL;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.85 mM) ; DMSO:25 mg/mL (73.13 mM)

Smiles

NC1 (Cc2ccc (Cl) cc2) CCN (CC1) c1ncnc2[nH]ccc12

Molecular Formula

C18H20ClN5

Molecular Weight

341.84

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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