GNF2133 hydrochloride
GNF2133 hydrochloride is a potent, selective, and orally bioavailable DYRK1A inhibitor (IC50: 6.2 nM) that enhances primary β-cell proliferation and insulin secretion. It is a valuable research tool for studying glucose homeostasis and pancreatic beta-cell regeneration in models of type 1 diabetes, based on in vitro and in vivo experimental data.
Product Specifications
CAS Number
2561414-57-9
Field of Research
Cell Biology, Signal Transduction
Smiles
Cl.CCN1CCN (CC1) C (=O) Nc1cc (ccn1) -c1cn (C2CCOCC2) c2cnccc12
Molecular Formula
C24H31ClN6O2
Molecular Weight
471.0
Storage Conditions
-20°C
Notes
For research use only.
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