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(R) -MALT1-IN-3

(R) -MALT1-IN-3 is a potent small molecule inhibitor of MALT1 protease, demonstrating an IC50 of 20 nM. It effectively suppresses IL-6 and IL-10 production in OCI-LY3 cells, making it a valuable chemical probe for researching MALT1-dependent signaling in lymphoma and autoimmune disease models.

Product Specifications

CAS Number

2504229-61-0

Field of Research

Immunology & Inflammation

Smiles

[C@H] (OC) (C=1C (NC (NC=2C=C (C (F) (F) F) C (=NC2) N3N=CC=N3) =O) =CN=C (C) C1C#N) C4CC4

Molecular Formula

C21H19F3N8O2

Molecular Weight

472.42

Storage Conditions

-20°C

Notes

For research use only.

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