(R) -MALT1-IN-3
(R) -MALT1-IN-3 is a potent small molecule inhibitor of MALT1 protease, demonstrating an IC50 of 20 nM. It effectively suppresses IL-6 and IL-10 production in OCI-LY3 cells, making it a valuable chemical probe for researching MALT1-dependent signaling in lymphoma and autoimmune disease models.
Product Specifications
CAS Number
2504229-61-0
Field of Research
Immunology & Inflammation
Smiles
[C@H] (OC) (C=1C (NC (NC=2C=C (C (F) (F) F) C (=NC2) N3N=CC=N3) =O) =CN=C (C) C1C#N) C4CC4
Molecular Formula
C21H19F3N8O2
Molecular Weight
472.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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