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RIPK1-IN-9

RIPK1-IN-9 is a potent and selective dihydronaphthone-based RIPK1 inhibitor, demonstrating high potency with IC50 values of 2 nM in U937 cells and 1.3 nM in L929 cells. This compound is a valuable chemical tool for investigating RIPK1-mediated necroptosis and inflammation in both cellular and animal models of disease.

Product Specifications

CAS Number

2682889-57-0

Product Name Alternative

RIPkinase, RIPK1, RIP kinase

Field of Research

Cell Biology, Signal Transduction

Purity

98.70% (May vary between batches)

Solubility

DMSO:4.73 mg/mL (10.01 mM)

Smiles

O=C1C=2C (=NC=C (C2) C3=CC=4N (C=C3) N=C (N) N4) CCN1CC5=C (OC6CCCC6) C=CC (F) =C5

Molecular Formula

C26H25FN6O2

Molecular Weight

472.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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