RIPK1-IN-9
RIPK1-IN-9 is a potent and selective dihydronaphthone-based RIPK1 inhibitor, demonstrating high potency with IC50 values of 2 nM in U937 cells and 1.3 nM in L929 cells. This compound is a valuable chemical tool for investigating RIPK1-mediated necroptosis and inflammation in both cellular and animal models of disease.
Product Specifications
CAS Number
2682889-57-0
Product Name Alternative
RIPkinase, RIPK1, RIP kinase
Field of Research
Cell Biology, Signal Transduction
Purity
98.70% (May vary between batches)
Solubility
DMSO:4.73 mg/mL (10.01 mM)
Smiles
O=C1C=2C (=NC=C (C2) C3=CC=4N (C=C3) N=C (N) N4) CCN1CC5=C (OC6CCCC6) C=CC (F) =C5
Molecular Formula
C26H25FN6O2
Molecular Weight
472.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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