FLT3-IN-14
FLT3-IN-14 is a potent small molecule inhibitor targeting both wild-type (IC50=5.6 nM) and ITD-mutant FLT3 (IC50=1.4 nM) . It suppresses FLT3 phosphorylation, induces G1 phase cell cycle arrest, and promotes apoptosis, making it a valuable tool for in vitro and in vivo research in acute myeloid leukemia.
Product Specifications
CAS Number
2620551-45-1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
N (C (NC=1C=C (C (C) (C) C) ON1) =O) C2=CC=C (C3=CN4C=5C=6C (CCC5SC4=N3) =CNC6) C=C2
Molecular Formula
C25H24N6O2S
Molecular Weight
472.56
Storage Conditions
-20°C
Notes
For research use only.
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