AAA-10

AAA-10 is a potent, orally bioavailable small molecule inhibitor of bacterial bile salt hydrolase (BSH) . It demonstrates high inhibitory activity against BSH from B. intestinalis (IC50: 10 nM) and B. longum (IC50: 80 nM) . This compound is a valuable research tool for investigating BSH function in gut microbiota-host interactions in both in vitro and in vivo models.