Emprumapimod
Emprumapimod (PF-07265803) is a selective, orally bioavailable p38α MAPK inhibitor that suppresses LPS-induced IL-6 production. It serves as a valuable research tool for investigating mechanisms and potential treatments for LMNA-related dilated cardiomyopathy in both cellular and animal models.
Product Specifications
CAS Number
765914-60-1
Product Name Alternative
ARRY-371797, p38MAPK, p38 MAPK, PF-07265803
Field of Research
Signal Transduction
Purity
99.10% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.97 mM) ; DMSO:80 mg/mL (168.95 mM)
Smiles
C (C (C) C) N1C=2C (=CC (OC3=C (F) C=C (F) C=C3) =C (C (N[C@@H] (CCN (C) C) C (N) =O) =O) C2) C=N1
Molecular Formula
C24H29F2N5O3
Molecular Weight
473.52
Storage Conditions
-20°C
Notes
For research use only.
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