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Emprumapimod

Emprumapimod (PF-07265803) is a selective, orally bioavailable p38α MAPK inhibitor that suppresses LPS-induced IL-6 production. It serves as a valuable research tool for investigating mechanisms and potential treatments for LMNA-related dilated cardiomyopathy in both cellular and animal models.

Product Specifications

CAS Number

765914-60-1

Product Name Alternative

ARRY-371797, p38MAPK, p38 MAPK, PF-07265803

Field of Research

Signal Transduction

Purity

99.10% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.97 mM) ; DMSO:80 mg/mL (168.95 mM)

Smiles

C (C (C) C) N1C=2C (=CC (OC3=C (F) C=C (F) C=C3) =C (C (N[C@@H] (CCN (C) C) C (N) =O) =O) C2) C=N1

Molecular Formula

C24H29F2N5O3

Molecular Weight

473.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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