IHMT-TRK-284
IHMT-TRK-284 (Compound 34) is a selective, orally bioavailable type II inhibitor of TRK kinases, demonstrating potent activity against TRKA, TRKB, and TRKC. It shows significant antitumor efficacy in vivo, making it a valuable chemical probe for researching TRK-driven cancers in both cellular and animal models.
Product Specifications
CAS Number
2416844-79-4
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (=C/C1=CC=CC=N1) \C=2C=3C (=CC (=CC3) C=4SC (NC (CN5CCN (C) CC5) =O) =NC4C) NN2
Molecular Formula
C25H27N7OS
Molecular Weight
473.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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