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IHMT-TRK-284

IHMT-TRK-284 (Compound 34) is a selective, orally bioavailable type II inhibitor of TRK kinases, demonstrating potent activity against TRKA, TRKB, and TRKC. It shows significant antitumor efficacy in vivo, making it a valuable chemical probe for researching TRK-driven cancers in both cellular and animal models.

Product Specifications

CAS Number

2416844-79-4

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

C (=C/C1=CC=CC=N1) \C=2C=3C (=CC (=CC3) C=4SC (NC (CN5CCN (C) CC5) =O) =NC4C) NN2

Molecular Formula

C25H27N7OS

Molecular Weight

473.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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