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SOS1-IN-8

SOS1-IN-8 is a potent SOS1 inhibitor with IC50 values of 11.6 nM and 40.7 nM against SOS1-G12D and SOS1-G12V mutants, respectively. This compound is a valuable research tool for investigating KRAS-driven cancers in both cellular and animal models.

Product Specifications

CAS Number

2759387-92-1

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

N ([C@H] (C) C1=C (F) C (C (CO) (F) F) =CC=C1) C=2C3=C (C=C (OC) C (O[C@H]4CCOC4) =C3) C (C) =NN2

Molecular Formula

C24H26F3N3O4

Molecular Weight

477.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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