FAK inhibitor 6
Compound 26F is a potent and selective enzyme inhibitor with an IC50 of 28.2 nM, exhibiting low cytotoxicity (IC50 = 3.32 μM) . It induces dose-dependent apoptosis and G0/G1 phase arrest in MDA-MB-231 cells, making it a valuable tool for cancer research, particularly in studying cell cycle regulation and programmed cell death in vitro.
Product Specifications
CAS Number
2410056-27-6
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
N (C=1N=C2C (=CSC2=CN1) C3=C (OC) C=CC=C3) C4=CC (F) =C (C (NC5CCNCC5) =O) C=C4
Molecular Formula
C25H24FN5O2S
Molecular Weight
477.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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