Cas9-IN-2
Cas9-IN-2 is a potent small-molecule inhibitor of the Cas9 nuclease, exhibiting an IC50 of 246 μM by binding to apo-Cas9 and preventing gRNA complex formation. This inhibitor serves as a valuable chemical tool for the precise temporal control of CRISPR-Cas9 activity in both in vitro biochemical assays and cellular research applications.
Product Specifications
CAS Number
1030133-34-6
Field of Research
Molecular Biology
Smiles
CN1C (C=2SC (C (=O) N3CCC (C) CC3) =C (C) N2) =CC (S (NC4=NOC (C) =C4) (=O) =O) =C1C
Molecular Formula
C21H27N5O4S2
Molecular Weight
477.6
Storage Conditions
-20°C
Notes
For research use only.
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