APJ receptor agonist 5
Compound 3 (APJ receptor agonist 5) is a potent, orally bioavailable apelin receptor agonist (EC50 = 0.4 nM) with favorable pharmacokinetics. It demonstrates efficacy in improving cardiac function in rodent heart failure models and has a suitable preclinical safety profile, supporting its use in cardiovascular disease research.
Product Specifications
CAS Number
2135514-20-2
Field of Research
Cardiovascular Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Smiles
C (OCC) C=1N (C (O) =C (C (=O) N2C[C@H] (CC2) C3=CC=CC=C3) C (=O) N1) C4=C (OC) C=CC=C4OC
Molecular Formula
C26H29N3O6
Molecular Weight
479.52
Storage Conditions
-20°C
Notes
For research use only.
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