KRAS inhibitor-13
KRAS inhibitor-13 is a potent and selective KRAS G12C inhibitor with an IC50 of 0.883 μM. It demonstrates downstream p-ERK inhibition in cellular models such as MIA PaCa-2 cells, supporting its research utility in pancreatic, colorectal, and non-small cell lung cancer studies.
Product Specifications
CAS Number
2230873-96-6
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (C=C) (=O) N1[C@@]2 ([C@@] (N (C2) C3=C4C (=NS3) C (F) =C (C (Cl) =C4) C=5C6=C (C=C (O) C5) C=CC=C6) (CC1) [H]) [H]
Molecular Formula
C25H19ClFN3O2S
Molecular Weight
479.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
