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KRAS inhibitor-13

KRAS inhibitor-13 is a potent and selective KRAS G12C inhibitor with an IC50 of 0.883 μM. It demonstrates downstream p-ERK inhibition in cellular models such as MIA PaCa-2 cells, supporting its research utility in pancreatic, colorectal, and non-small cell lung cancer studies.

Product Specifications

CAS Number

2230873-96-6

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

C (C=C) (=O) N1[C@@]2 ([C@@] (N (C2) C3=C4C (=NS3) C (F) =C (C (Cl) =C4) C=5C6=C (C=C (O) C5) C=CC=C6) (CC1) [H]) [H]

Molecular Formula

C25H19ClFN3O2S

Molecular Weight

479.95

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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