LX-039
LX-039 is a potent and selective oral estrogen receptor degrader (SERD) with an EC50 of 2.99 nM, featuring an indole C-3 chloride substitution. It demonstrates favorable pharmacokinetics with low clearance and high oral exposure in mice, supporting its investigation for antitumor efficacy in breast cancer research models.
Product Specifications
CAS Number
2135341-09-0
Field of Research
Metabolism Research
Smiles
C (=C (CC) C1=C (Cl) C=C (F) C=C1) (C2=C (Cl) C=3C (N2) =CC=CC3) C4=CC=C (C=CC (O) =O) C=C4
Molecular Formula
C27H20Cl2FNO2
Molecular Weight
480.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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