EGFR-IN-47
EGFR-IN-47 is a potent, orally bioavailable inhibitor targeting the EGFRL858R/T790M/C797S mutant with an IC50 of 0.01 μM. It demonstrates anti-tumor activity by inducing cell cycle arrest and apoptosis in vitro, supporting its investigation for non-small cell lung cancer (NSCLC) in preclinical research.
Product Specifications
CAS Number
3034649-73-2
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.78% (May vary between batches)
Smiles
N1=CC=2C=C (N (C2N=C1NC3=CC=C (C=C3) N4CCN (C) CC4) C5CCCC5) CNC=6C=CC=CC6
Molecular Formula
C29H35N7
Molecular Weight
481.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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