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EGFR-IN-47

EGFR-IN-47 is a potent, orally bioavailable inhibitor targeting the EGFRL858R/T790M/C797S mutant with an IC50 of 0.01 μM. It demonstrates anti-tumor activity by inducing cell cycle arrest and apoptosis in vitro, supporting its investigation for non-small cell lung cancer (NSCLC) in preclinical research.

Product Specifications

CAS Number

3034649-73-2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

98.78% (May vary between batches)

Smiles

N1=CC=2C=C (N (C2N=C1NC3=CC=C (C=C3) N4CCN (C) CC4) C5CCCC5) CNC=6C=CC=CC6

Molecular Formula

C29H35N7

Molecular Weight

481.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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