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SOS1 activator 1

SOS1 activator 1 is a small molecule that potently activates the SOS1 guanine nucleotide exchange factor (Kd = 44 nM), promoting the exchange of GDP for GTP on RAS proteins. This tool compound is used in vitro and in vivo to investigate RAS signaling pathways in cancer research and cellular biology.

Product Specifications

CAS Number

2245237-53-8

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

C (N1C (=NC=2C1=CC (Cl) =CC2N3CCN (C) CC3) N4CC5 (C4) CNC5) C6=CC (C) =C (F) C (C) =C6

Molecular Formula

C26H32ClFN6

Molecular Weight

483.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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