HSP90-IN-13
HSP90-IN-13 is a potent, broad-spectrum HSP90 inhibitor (IC50 = 25.07 nM) with additional activity against EGFR, VEGFR-2, and Topoisomerase II. It induces G2/M cell cycle arrest and triggers mitochondrial apoptosis in MCF-7 breast cancer cells, supporting its investigation in oncology research for in vitro mechanistic studies.
Product Specifications
CAS Number
2446055-29-2
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction
Smiles
C (N1C (SCC2=CN (N=N2) C3=CC (C (O) =O) =CC=C3) =NC=4C (C1=O) =CC (C) =CC4) C5=CC=CC=C5
Molecular Formula
C26H21N5O3S
Molecular Weight
483.54
Storage Conditions
-20°C
Notes
For research use only.
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